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RETICULON 4 RECEPTOR
Descriptors Found:
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DeCS
Descriptor
English
:
Nogo Receptor 1
Descriptor
Spanish
:
Receptor Nogo 1
Descriptor
Portuguese
:
Receptor Nogo 1
Synonyms
English
:
NgR1 Protein
Nogo 66 Receptor
Nogo-66 Receptor
Protein, NgR1
Protein, RTN4R
RTN4R Protein
Receptor, Nogo-66
Receptor, Reticulon-4
Reticulon 4 Receptor
Reticulon-4 Receptor
Tree Number:
D12.776.395.550.448.738.500
D12.776.543.484.500.738.500
D12.776.543.550.418.738.500
D12.776.543.750.600.500
D12.776.631.651.500
Definition
English
:
A high affinity receptor for myelin-associated inhibitors (MAIs) that include NOGO-A PROTEIN;
OLIGODENDROCYTE MYELIN GLYCOPROTEIN
; and
MYELIN-ASSOCIATED GLYCOPROTEIN
. It is expressed primarily by
neurons
in the brain and OLFACTORY BULBS. During
embryonic development
, it is expressed in the
PERIPHERAL NERVOUS SYSTEM
. It localizes to
GROWTH CONES
and may inhibit
neurite
outgrowth following SPINAL INJURY.
History Note
English
:
2017
Allowable Qualifiers
English
:
AD
administration & dosage
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PH
physiology
RE
radiation effects
TU
therapeutic use
UL
ultrastructure
Record Number:
56628
Unique Identifier:
D000070816
Occurrence in VHL
:
Similar:
DeCS